Robust tube-based predictive control of blood glucose concentration in type 1 diabetes
52nd IEEE Conference on Decision and Control (CDC), pp. 2084-2089, 2013
Author(s): | Kirchsteiger H., Del Re L. |
Year: | 2013 |
Month: | 12 |
Abstract: | This paper investigates the applicability of tubebased
robust MPC to control the blood glucose concentration
in type 1 diabetic subjects through simulation studies. An
existing, widely used metabolic simulation model is adopted and
extended with several physiologically motivated uncertainties to
account for the underlying intra?patient variability observed in
real patients. Results on a virtual subject show that robustness
to uncertainties can be improved and the risk of hypoglycemia
reduced, without increasing the online computational demands
compared to the conventional model predictive control approach. |